Autoregulation of RANK ligand in oral squamous cell carcinoma tumor cells
نویسندگان
چکیده
منابع مشابه
A novel function of CXCL13 to stimulate RANK ligand expression in oral squamous cell carcinoma cells.
Oral squamous cell carcinomas (OSCC) are malignant tumors with a potent activity of local bone invasion/osteolysis. The chemokine ligand, CXCL13, has been identified as a prognostic marker for OSCC development and progression. Here in, we show that recombinant hCXCL13 treatment of OSCC cells stimulates (5-fold) RANK ligand (RANKL), a critical bone resorbing osteoclastogenic factor expression. A...
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ژورنال
عنوان ژورنال: Journal of Cellular Physiology
سال: 2018
ISSN: 0021-9541,1097-4652
DOI: 10.1002/jcp.26456